nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma
نویسندگان
چکیده
منابع مشابه
nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma.
BACKGROUND The discovery that genetic alterations in oncogenes and tumour suppressor genes accompany tumour formation in many human tumours has encouraged the search for genes that promote or suppress tumour spread and metastasis; nm23 is a promising candidate for a metastasis suppressing gene. AIMS To evaluate whether expression of nm23-H1 protein or loss of heterozygosity (LOH) of the nm23-...
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It has previously been reported that intratumoral microvessel density (IMD), and the expression of bFGF and nm23-H1 are useful prognostic markers in colorectal cancer (CRC). In this study, a total of 100 CRCs were evaluated histopathologically, and IMD, bFGF and nm23-H1 expression were assessed by immunohistochemistry. IMD of patients increased with grade and stage, and this increase was statis...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2004
ISSN: 0021-9746
DOI: 10.1136/jcp.2004.017954